• New publication on RIG-I like receptors
    We have a new paper coming out in Protein Science: Zerbe, C.M., Mouser, D.J. and Cole, J.L. (2019) Oligomerization of RIG-I and MDA5 2CARD Domains. Protein. Sci., in press.
  • Cassie Zerbe, Ph.D.
    Cassie Zerbe did a great thesis defense presentation on October 8 and is now Dr. Cassie Zerbe.
  • Emphutos Therapeutics
    Jim has formed a company, Emphutos Therapeutics, to develop novel antiviral agents that target the host immunity pathway.

Recent Publications

Mayo, C.B., Erlandsen, H., Mouser, D.J., Feinstein, A.G., Robinson, V.L., May, E.R., Cole, J.L. (2019) Structural basis of protein kinase  autophosphorylation. Biochemistry, in press.

Maniaci, B., Lipper, C. H., Anipindi, D. L., Erlandsen, H., Cole, J. L., Stec, B., Huxford, T. and Love, J.J.(2019).  Design of High-Affinity Metal-Controlled Protein Dimers. Biochemistry, 58, 2199–2207.

Pindrus, M.A., Cole, J.L., Kaur, J., Shire, S.J., Yadav, S. and Kalonia, D.S. (2017) Effect of aggregation on the hydrodynamic properties of bovine serum albumin. Pharm. Res. 34. 2250–2259.

Mayo, C.B. and Cole, J.L. (2017) Interaction of PKR with single-stranded RNA. Sci Rep. 7, 3335. 

Mayo, C.B., Wong, C.J., Lopez P.E., Lary, J.W. and  Cole, J.L. (2016) Activation of PKR by short stem-loop RNAs containing single-stranded arms. RNA 22, 1065-1075. doi:10.1261/rna.053348.115.


Phone: (860) 486-4333
Address: 91 North Eagleville Road
Storrs, Connecticut 06269-3125