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Research Overview

Our group uses biophysical approaches to characterize macromolecular interactions that regulate important biological processes. We focus on host-virus interactions that are ammenable to therapeutic intervention. Our main tool is analytical ultracentrifugation, but we also make extensive use of fluorescence, calorimetry, light scattering and small angle X-ray and neutron scattering.

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Sedimentation Velocity Analysis
(Anderson et al., 2011)

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PKR Dimer (Dar et al., 2005)

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contact: James Cole
Last updated: June 12, 2014